L-00 Daily Defense Cleanser — Waitlist

The daily exposome reset.
A gel-to-foam cleanser that clears the day's pollution, hard-water metals, sunscreen and grime — without stripping your barrier.
First access on launch day.
Every cleanser makes you choose.
Skin doesn't only age from your genes. It ages from what it meets every day.
Scientists call the sum of these daily exposures the exposome.1 Here's what's on your face by the end of the day:
Left on overnight, this load drives oxidative stress in skin.4 L-00 clears it every day — before it adds up.

Bind. Lift. Protect.
14 ingredients. Three jobs.
Cleansing is barrier preservation.
Your barrier is your longevity organ. When it's damaged, skin loses water and runs low-grade inflammation. In older skin, a weaker barrier comes with more of that inflammation.7 Harsh cleansing damages the barrier every single day.5
Two steps. Defend + Repair.
Everything you need. Nothing you don't.
Be first to reset.
Join the waitlist and get L-00 the day it launches.
- Krutmann J, Bouloc A, Sore G, Bernard BA, Passeron T. The skin aging exposome. J Dermatol Sci. 2017;85(3):152–161.
- Vierkötter A, Schikowski T, Ranft U, et al. Airborne particle exposure and extrinsic skin aging. J Invest Dermatol. 2010;130(12):2719–2726.
- Danby SG, Brown K, Wigley AM, et al. The effect of water hardness on surfactant deposition after washing and subsequent skin irritation in atopic dermatitis patients and healthy control subjects. J Invest Dermatol. 2018;138(1):68–77.
- Mancebo SE, Wang SQ. Recognizing the impact of ambient air pollution on skin health. J Eur Acad Dermatol Venereol. 2015;29(12):2326–2332.
- Ananthapadmanabhan KP, Moore DJ, Subramanyan K, Misra M, Meyer F. Cleansing without compromise: the impact of cleansers on the skin barrier and the technology of mild cleansing. Dermatol Ther. 2004;17(Suppl 1):16–25.
- Fluhr JW, Darlenski R, Surber C. Glycerol and the skin: holistic approach to its origin and functions. Br J Dermatol. 2008;159(1):23–34.
- Hu L, Mauro TM, Dang E, et al. Epidermal dysfunction leads to an age-associated increase in levels of serum inflammatory cytokines. J Invest Dermatol. 2017;137(6):1277–1285.
L-00 Daily Defense Facial Cleanser · 236 ml / 8 fl. oz.

